My research focuses on membrane transporters, which are of great importance to drug disposition and response. I am particularly interested in genetic variants in membrane transporters that are determinants of drug response and in harnessing transporters to enhance drug targeting.
I am a biophysicist. My research is focused on discovering the macromolecular structure and dynamics of proteins—defining conformational states essential for function and understanding transitions between these states.
I am a bioengineer focusing on micro and nanofabrication techniques to create new devices for drug and cell delivery as well as biomaterials for cell and tissue regeneration. I also chair the Department of Bioengineering and Therapeutic Sciences.
I study molecular genetics and signaling pathways in liver cancer development with the goal to develop better targeted therapy for this deadly malignancy.
I am a physician-scientist with training in pulmonary medicine, genetics, and epidemiology. My research and academic interests center on identifying disease risk factors specific to racial groups, most especially those related to asthma and drug response. I am engaged in a new, international field of study relating ancestry and genetic susceptibility to specific diseases and varying drug response.
Video of Science Bulletins: Genes and Health—Moving Beyond Race
My work in computational biology is aimed at learning how nature has evolved the enzyme reactions necessary for life. I use that knowledge to guide enzyme engineering in the lab, leading to the discovery of new reactions and the improvement of function prediction.
