From molecular discovery to therapeutic innovation, we combine bioengineering with computational science to develop personalized treatments. Our research integrates genetic analysis, advanced biomarker detection, and quantitative modeling to accelerate the development of precise, effective therapies. See all of our research areas.
Advancing drug discovery and treatment optimization through computational modeling and systems-level analysis of biological processes.
Understanding how genetic variation impacts drug response to enable more precise and personalized therapeutic strategies.
Understanding how genetic variation impacts drug response to enable more precise and personalized therapeutic strategies.
Understanding how genetic variation impacts drug response to enable more precise and personalized therapeutic strategies.
$30M
14,000
Pioneering the analysis of over 14,000 biosynthetic gene clusters across 2,500 human-associated bacteria to discover new therapeutic compounds.
46th year
In 2025, and for the 46th consecutive year, the UCSF School of Pharmacy received more research funding from the National Institutes of Health (NIH) than any other pharmacy school.
Education
Postdoctoral scholars, specialists, and researchers (PSRs) from across the UCSF School of Pharmacy gathered at the Wayne and Gladys Valley Center for Vision on the Mission Bay campus on June 24, 2026, for the third annual PSR Symposium, an inspiring day of scientific exchange, career development, and community building hosted by the Center for Collaborative Innovation (CCI).
Leslie Benet, PhD ’65, professor emeritus in the UCSF School of Pharmacy Department of Bioengineering and Therapeutic Sciences, spent 61 years reshaping how medicines are dosed worldwide and mentoring budding scholars. Yet in a career marked by nearly every major award in pharmaceutical science, he's most excited about what he's doing today.
A UCSF research team led by Department of Bioengineering and Therapeutic Sciences Chair and Professor James Fraser, PhD and Department of Pharmaceutical Chemistry Professor William DeGrado, PhD, has pioneered a breakthrough approach to designing proteins with targeted functions, which could lead to simpler ways to improve enzymes and medications, among other uses, according to a new study published in Nature Chemistry.