Our scientists understand how difficult it is to develop new therapeutics. In industry, the process is complicated and fraught with failure. The goal is to make the process more efficient and improve success.
The drug development process includes and requires evaluation of safety and efficacy. The process begins long before a candidate drug is tested in patients and extends through the lifecycle of a drug long after it is available to patients in the market. Our scientists are expert along this full continuum and conduct research in:
- Drug absorption, distribution, metabolism, and excretion characteristics and toxicity
- Drug safety
- Efficacy of a candidate drug through studies of its pharmacokinetic and pharmacodynamic properties in patient populations
- Biomarker selection
- Clinical trial design and analysis
- Modeling
- Simulation
- Regulatory sciences needed to optimize the drug development process.
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 | Adam Abate, PhD
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 | Nadav Ahituv, PhD
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 | Patsy Babbitt, PhD Joint appointment:
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 | Les Benet, PhD Joint appointment:
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 | Frances Brodsky, PhD Joint appointments:
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 | Esteban González Burchard, MD, MPH Joint appointment:
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 | Xin Chen, PhD
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 | Tejal Desai, PhD
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 | Michael Fischbach, PhD
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 | Leslie Floren, PharmD
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 | Kathy Giacomini, PhD Joint appointments:
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 | Su Guo, PhD Joint appointment:
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 | Ryan Hernandez, PhD
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 | Betty-Ann Hoener, PhD Joint appointment:
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 | Yong Huang, PhD
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 | C. Anthony Hunt, PhD
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 | Ajay Jain, PhD Joint appointment:
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 | Tanja Kortemme, PhD
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 | Deanna Kroetz, PhD Joint appointment:
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 | Emil Lin, PhD
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 | Sarah Nelson, PhD
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 | Shuvo Roy, PhD
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 | Andrej Sali, PhD Joint appointment:
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 | Nancy Sambol, PharmD Joint appointment:
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 | Rada Savic, PhD
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 | Francis Szoka, PhD Joint appointment:
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 | Chao Tang, PhD Joint appointment:
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 | Davide Verotta, PhD Joint appointment:
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