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PSPG
245A
Basic Principles of Pharmaceutical Sciences
(required)
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(3
units) This course is focused on fundamental mechanisms of
membrane transport, pharmacokinetics, modeling, and quantitation
of these processes.
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PSPG
245B.
Basic Principles of Pharmaceutical Sciences
(required)
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(3
units) This course is focused on basic mechanisms of pharmacology,
toxicology, and drug metabolism barriers to drug delivery.
Emphasis is placed on modeling and quantitative aspects of
these processes.
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PSPG
245C.
Basic Principles of Pharmaceutical Sciences
(required)
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(2
units) An introduction into the genetic factors underlying
the efficacy and toxicity of drugs. Topics to be covered include
genomic methods in drug design, drug development and drug
therapy.
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Chem
241. Molecular Thermodynamics
(one of five core electives
from which a student must select two that
complete their core program)
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(5
units) This is a course on molecular thermodynamics and statistical
mechanics. It covers the concepts of entropy, enthalpy, heat
capacity, free energy, ligand binding, solvation, the properties
of water, the hydrophobic effect, solution electrostatics,
adsorption, and physical and chemical kinetics.
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Chem
243. Molecular Biochemistry
(one
of five core electives from which a student must select two
that
complete their core program)
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(5
units) Basics of molecular biochemistry with a particular
emphasis on understanding and manipulating molecular mechanisms
of complex biochemical phenomena. Lectures will address macromolecular
structure, function, mechanisms, synthesis and metabolism
applications.
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Genetics
200A. Principles of Genetics
(one of five core electives
from which a student must select two that
complete their core program)
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(3
units) In-depth analysis of genetic mechanisms in selected
prokaryotes, eukaryotes Topics include genetic exchange (conjugation,
generalized and specialized transduction, transformation),
recombination (general, site-specific), mapping,
mutagenesis (induction and consequences), mobile genetic elements,
gene expression, meiotic and mitotic segregation, allelism,
position effects.
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BMI
206. Introduction to Bioinformatics
(one of five core electives
from which a student must select two that
complete their core program)
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(3
units) Basic concepts in genome biology and molecular evolution
relevant to bioinformatics. Generation and annotation of genetic
information. Types, organization and uses of bioinformatics
databases, database searching and evaluation of results.
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BMS
255. Basic Genetics & Genomics
(one
of five core electives from which a student must select two
that
complete their core program)
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(4 units)
The scope of this graduate level course in genetics is to
convey an understanding of basic genomics and molecular genetics,
of the use of genetic animal model systems and of the analytical
principles of simple and complex human genetic traits.
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PSPG
206:
Laboratory Rotations
(Two
rotations are required during year one)
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(1-8
units) This course covers laboratory rotations, which are a key aspect
of the interdisciplinary research training program. Rotations
provide valuable exposure to the diversity of the program
and allow students to gain firsthand experience to aid in
choosing a research advisor and thesis laboratory.
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PSPG
220:
Research Conference
(required)
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(1
unit) This course affords students the opportunity to develop
and polish their presentation skills. All students-second
year and above-present their work to other students, postdoctoral
fellows, and faculty, are critically evaluated, and are given
constructive feedback.
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PSPG
225:
Graduate Research Opportunities
(required;
offered during the fall and winter quarters)
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(1
unit) A series of weekly presentations of the research interests
of the basic science faculty. The purpose is to acquaint new
graduate students with the research in the PSPG program.
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PSPG
250:
Research
(required)
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(1-8
units) This course reflects students' dissertation research.
May be taken when at least two laboratory rotations have been completed.
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PSPG
266:
Research Planning Conference
(required)
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(1
unit) This course reflects students' participation in laboratory
meetings during their rotations.
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PSPG
299:
Dissertation
(required)
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(1-8
units) This course reflects students' dissertation research
during the final quarter.
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Biostatistics
183
(required) |
This
course provides an introduction to the use of statistical techniques
in biomedical and behavioral research. The course will cover
common descriptive statistics including the mean, median and
standard deviation, as well as techniques for testing hypotheses
(analysis of variance, t-tests, regression, nonparametric methods)
and issues in sampling and design of experiments. |
| Biochem
244. Scientific Conduct
(required)
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(1 unit) Course covers the basic principles of ethical scientific
conduct in a modern biomedical research laboratory. Lectures
will be followed by small group discussions focusing on sample
cases illustrating key ethical issues. |
BMS
260. Cell Biology
(elective) |
(4
units) The scope of this Cell Biology course is to convey an
understanding of the function and the organization of molecules
and organelles inside and outside the cell, and how these are
used to construct a multicellular tissue and organ. The course
concentrates on major principles of cell biology that are derived
from experimentation and on powerful new tools that have informed
us of these concepts at more detailed levels of resolution.
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PIBS
245. Cell Biology
(elective) |
(4
units) Modern aspects of the molecular basis of cell function
are examined with emphasis on how cells move, secrete, divide
and communicate with each other.
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BMI
203. Introduction to Biomedical Computing
(elective)
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(2
units) An introductory course covering basic concepts, terminology
and applications in biomedical computing. Topics include computational
biology (protein structure prediction and folding, molecular
structure and energy calculations, docking) computer graphics
and molecular graphics and the mathematical modeling of biologically
dynamic systems.
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PSPG
271. Advanced Pharmacokinetics in Clinical Drug Development
(elective)
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(4 units)
Although significant time will be devoted to theoretical aspects
of the various topics, the focus will be on practical examples
(real data) in how to design and interpret pharmacokinetic studies
for use as a component of the regulatory drug approval process.
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PSPG
272A. Advanced Drug Delivery: Controlled and
Targeted Drug Delivery
(elective)
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(2 units)
The focus of this course is on the chemical, biophysical and
biological factors that impact on targeted and controlled
drug delivery systems. There is a particular emphasis on colloidal
systems and system that provide a regulated controlled release.
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PSPG
272B. Advanced Drug Delivery: Nanosystems
(elective)
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(2 units)
A lecture and discussion course that presents the pharmacokinetic
and dynamic factors that impact drug delivery and drug targeting
using nanosystems and intelligent materials.
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