Xin Chen's Lab

Lab Members

Xin's photo

Xin Chen, Ph.D., PI

Xin received her Bachelor of Medicine degree at Beijing Medical University. She came to the US immediately after graduating from medical school and joined the BBS program of the Division of Medical Sciences at Harvard University. She worked with Dr. Malcolm Whitman of the Cell Biology Department and studied TGF-beta signaling in early Xenopus development. She cloned FAST-1, which is the first transcriptional factor that interacts with Smad proteins to transduce TGF-beta signals. After obtaining her Ph.D., Xin moved to California and worked with Dr. Patrick Brown at Stanford University as a postdoctoral fellow. Her research focuses on genomic analysis of human gastrointestinal tumors, mainly liver and gastric cancers.   In 2003, she became an Assistant Professor at the Department of Biopharmaceutical Sciences, UCSF.   She is continuing her research in molecular genetics and genomics of GI tumors, and together with Dr. Kathy Giacomini is also expanding her projects to pharmacogenomics of chemotherapeutic agents. (Profile)

   
Lijie Jiang (Holly), Lab Manager & Assistant Specialist
Holly obtained her Bachelor degree at Qingdao Agricultural University, and her Master Degree at Zhejiang University. Holly joined our lab in July 2009. She is an expert in molecular biology and cloning. Since early 2011, She became our new lab manager.
   
Chunmei Wang (Maggie), Ph.D., Postdoc Fellow
Maggie joined our lab in September 2009. She received her Ph.D. in molecular genetics from Institute of Genetics and Developmental Biology, Chinese Academy of Sciences in 2008. Before joining Chen's lab, Maggie worked as a research fellow at Beijing 302 Hospital. Her current project focuses on the role of PI3K/AKT/mTOR signaling pathway in the HCC tumorigenesis.
   
Bing Gui, Staff Research Associate
Bing joined Dr. Chení»s lab in May 2011 as a volunteer. In Nov 2011, he became a staff research associate to participate in the alcohol project. He also takes care of the lab computers and webpage.
   
Li Lei (Lucy), Ph.D., Visiting Scholar
Joined us in 2011, Lucy is a visiting scholar from Huazhong University of Science and Technology, Wuhan. She received her Doctor of Science degree in Biotechnology from Wuhan University in 2005. Her current research focuses on elucidating the functional role of FASN and SREBP in the HCC tumorigenesis signaling pathway. Lucy is currently an Assistant Professor at Tongji Medical Universit in China.
   
Junyan Tao, Ph.D., Postdoc Fellow
Junyan joined Dr. Chen's lab in Mar 2012. He received his Ph.D. in College of Life Science & Technology, Huazhong University of Science and Technology, Wuhan. Before joining in Chen's lab, Junyan worked as a teacher at Hubei University of Traditional Medicine, and worked as a postdoc research associate fellow in Texas A&M University from August, 2011. His current project mainly focuses on the role of Hippo/Yap signaling pathway in HCC tumorigenesis in vivo and in vitro model, the molecular mechanisms of alcohol involved in HCV or HBV infection induced HCC tumorigenesis in mouse model.
   
Chencheng Xie (Gabriel), Visiting Graduate Student
Chencheng Xie(Gabriel) was enrolled in Huazhong University of Science and Technology (HUST) in Sep. 2005, majoring in Clinical Medicine of Eight-Year Education System, and he joined our lab in April 2012. His current work focuses on glycolysis pathways, including the role of HIF1a, HK2 and PKM2 during liver cancer development.

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